I would say it's sort of like a good sounding cranked Plexi. However like all Z amps it has that Dr. Z sound & feeling. It's a very open sounding amp The string to string definition is VERY good. Touch sensitivity is very nice as well. Cleans up real nice & you can get tons of different gain/drive sounds just by tweaking your guitars volume knob. It's also not forgiving of sloppy playing. The low end response can get very heavy if your into a big low end thump. The mids are smooth and cut through nicely. The highs are also very smooth & don't sound shrill or thin even when turned way up. The tone controls are very interactive & a little tweak can really change the tone. The 6545 sounds good @ "bedroom" levels but it really shines @ band volume levels. I mean it comes alive in a BIG way. Lead tones are there as well. For my taste I am going to use something like an RC Booster to give myself just a little bump in my lead volume without changing the tone. The 6545 is a great amp. At this point in my playing it is all that I am looking for & I expect it to be around for a long time. If you are interested in trying one call Midtown Music. They allow you a 48 hr "approval" period. You try the amp, you don't like it, you send it back, no restocking fees no problem as long as the amp is returned in the same condition.